RNA transcripts, MicroRNAs, mRNA, and sRNAs

A primary transcript is the single-stranded ribonucleic acid (RNA) product synthesized by transcription of DNA, and processed to yield various mature RNA products such as mRNAs, tRNAs, and rRNAs

  • RNA polymerase, together with one or more general transcription factors, binds to promoter DNA
  • RNA polymerase generates a transcription bubbleRNA polymerase adds RNA nucleotides
  • RNA sugar-phosphate backbone forms with assistance from RNA polymerase to form an RNA strand
  • Hydrogen bonds of the RNA–DNA helix break, freeing the newly synthesized RNA strand

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