Nucleosome positioning

nucleosome positioning” broadly to indicate where nucleosomes are located with respect to the genomic DNA sequence. Although nucleosome positioning is a dynamic process, sequencing-based mapping approaches identify the positions of individual nucleosomes in a single cell at a specific time.

 

  • Nucleosome positioning is strongly affected byDNA sequence
  • Poly tracts are important for nucleosome depletion
  • Aspects of positioning not determined by DNA sequence

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