Epigenetics and Chromosome

Need of Epigenetic Biomarkers

    The epigenome describes to the complete description of all potentially heritable modifications of the genome without any changes in primary DNA sequences. Epigenetic biomarkers can be widely defined as measurable modifications of the genome with preserved DNA sequence.

    Epigenetic manupulation and regulators represent potential molecular elements which control relevant physiological and pathological features, thereby contributing to the natural history of human disease. These epigenetic modulators can be used as disease biomarkers, since they show several advantages and provide information about gene function, thus explaining differences among patient endophenotypes.

    Noninvasive Epigenetic Markers can be used as biomarkers for the molecular diagnosis of following cancer: