Brain disorders & Epigenetics

    Neurodevelopmental disorders/diseases are a group of disorders in which the development of the central nervous system is disturbed. This can include brain dysfunction, which can manifest as neuropsychiatric   problems or impaired motor function, learning, language or non-verbal communication.

 

   This field of research provides evidence that environmentally induced epigenetic changes during embryonic development can be transmitted for multiple generations and may contribute to the etiology of brain disease heritability. In this review, we discuss some of the most updated findings on transgenerational epigenetic inheritance. We particularly discuss the upcoming findings on the epigenetic mechanisms involved in the heritability of alcohol-induced neurobehavioral disorders such as fetal alcohol spectrum disorders.

 

  • Therapeutic epigenetic-driven approaches to treat psychiatric disorders
  • Epigenetic link between psychiatric disorders and dementia
  • Epigenetic contributions to neurogenesis induction during ageing

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