Epigenetic Therapy

Epigenetic therapy is meant to use the drugs or Epigenome - influencing techniques to treat medical states. Histone Deactylases(HDACs), which modify histones, and DNA Methyltransferases(DNMTs), which methylate DNA are the two enzymes that are important in epigenetic modifications and key targets for therapy with pharmaceutical drugs. Successful clinical studies carried out for both the enzymes. Epigenetic therapy has shown a strong effectiveness against Hematological Malignancies and Solid Tumors, gaining FDA approval for cutaneous T-cell Lymphoma, ER-positive metastatic Breast Cancer, Myelodysplastic Syndrome, multiple myeloma, and peripheral T-cell lymphoma. Epigenetic Therapy has proven successful for several types of cancer, including Lung Cancer, breast cancer, and Lymphoma.

1. Fear

2. Anxiety

3. Trauma

4. Cardiac dysfunction

5. Schizophrenia

6. Pharmacokinetics Epigenetics

 

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