Epigenetic Methylation

Epigenetics Methylation refers to the addition of a methyl group (CH3) to the base Cytosine (C) using covalently bond in the dinucleotide 5´-CpG-3´. Mostly the CpG Dinucleotides in the human genome are methylated and the Unmethylated CpGs are not distributed randomly, but are usually clumped together in ‘CpG islands, which are in the -region that facilitates transcription of a particular gene.

1. DNA Methyltransferases

2. Molecular cloning

3. DNA methylation marks

4. Differentially methylated regions (DMRs)

 

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