Professor & Director of Institute of Toxicology
University Medical Center
Bernd Kaina completed his PhD in Genetics from Universtity of Halle, Germany in 1976. He completed his Postdoctoral training at the Institute of Genetics in Gatersleben and continued his studies on DNA repair in the Department of Molecular Biology in Leiden, Netherlands and at the German Cancer Research Center in Heidelberg and, as a Heisenberg Fellow in the Department of Genetics of the Nuclear Research Center in Karlsruhe, Germany. In 1993, he obtained a full professorship at Institute of Toxicology of the University of Mainz and, since 2003; he acts as a Director of the Institute. His research program focuses on MGMT and the regulation of repair genes, DNA damage signaling, genotoxicity, cancer formation and death of cells exposed to radiation, chemical genotoxins and anticancer drugs. In a translational research program, his group studies the mechanisms of resistance of glioma, melanoma and other cancer cell types to alkylating anticancer drugs.